Lars why so serious

What usually comes first for you? I feel like I write very carefully. Ulrich: It was a very transitional, experimental time. It was just this fucking machine. And then [James] Hetfield had to go away and deal with some of his [substance abuse] issues, and then that opened up this whole thing. It was a difficult time with Phil.

And as easy as a target as he is to make fun of, whenever I get asked about it now, I find myself defending him. He did save the fucking band. Bridgers: Also, St. Anger is a great record. It might have been the first Metallica album I heard. Ulrich: That record had a very, very different makeup. For those couple years, everything was about being open with each other, about the spirit of no rules. To still do something that not even turns other people on, but turns me on. I hope it goes better than what I did.

Back in the late Nineties, early s, I had an imprint through Elektra Records. One of the ones I put out was the least-selling record. Bridgers: Yeah, send shit my way! Want more Rolling Stone? Sign up for our newsletter. Newswire Powered by. We started setting up, and waltzing around a few musical things, and he was complaining about how loud we were and that we were playing everything wrong.

Every single thing we were doing was wrong. It wasn't limited to our entire approach to music, our existence was wrong. From the day we were born, our existence was wrong. Obviously I'm exaggerating for effect here …. But within an hour or so, me and him had a little chat, and I think I comforted him in the fact that nothing bad was going to happen. It dawned on me when I was talking to someone else about Lou, that a lot of people from his generation, they've just been so mistreated over the years by people who have taken advantage of them, both inside and outside the business — a lot of people his age are guarded.

So when a bunch of musicians in their 40s welcome him with open arms and invite him to come in and jam, he's just suspicious that something's going to happen. I understand that and I'm not faulting him for that.

Things did thaw, me and him had a pow-wow in a corner, and it went very fast and became pretty cool. We realised we had so much in common. There was this trust. But he was a very guarded, mistrusting person, and spending the subsequent couple of years with him and being around everything from interviews to playing gigs I could just see that whenever there were new people who came on his radar that he would have to size them up first before he let himself be opened up.

I've met half a dozen other artists from his generation, and if you talk to them for long enough they'll tell you stories about getting fucked over, by the man, the system, the business, bad deals, each other, whatever. We were both outsiders, we both never felt comfortable going down the same path that everyone else was doing. Metallica's always been autonomous, and Lou Reed is the godfather of being an outsider, being autonomous, marching to his own drum, making every project different from the previous one and never feeling like he had a responsibility to anybody other than himself.

We shared kinship over that. And we brought him something that he didn't have, or maybe hadn't experienced so much, which in his own words were 'energy' and "weight" and "size" and whatever it is that happens when we start playing. He was so into what we brought him.

And, of course, he brought us this incredible piece of work that he had already written, Lulu , and about her escapades and sexual endeavours.

We brought something to each other , and we shared a common lack of ability to fit in with our surroundings. Reading on mobile? Click to view. Jann Wenner threw a celebration of the Rock'n'Roll Hall of Fame, and U2 and Springsteen were there hosting little segments, and they asked us to host a segment, so we asked him to play with us.

And that worked out very well, and I think he felt so comfortable with us. Novo is aiming to launch a new era of obesity management with a new approval for semaglutide. You have forecast a growing amount of sales. And I wanted to start off by asking you about obesity in particular. Semaglutide has been approved in the United States for obesity.

There have been weight loss drugs that have come along. Confirming one of the worst kept secrets in Washington, news reports are ricocheting through the Beltway that Robert Califf will be nominated later today to lead the FDA for a second time. This blog post is the second in a series about accelerating the development and manufacturing of cell-based cancer therapies. In the last post , we outlined the promise and potential of immune cell therapies to treat cancer along with an overview of the central challenges that impede their broad accessibility.

In this article, we take a closer look at key considerations for establishing a reliable supply chain of quality materials to ensure a robust and reproducible workflow.